Fengsui Dan first appeared in “Qixiao Liangfang”writed by Dong Su in Ming dynasty and Qianyang Dan was invented by Zheng Qinan in Qing dynasty,but later medical scientists often use the two together,which is called Qianyang Fengsui Dan by Wu Pei-heng. Professor Wu Sheng-yuan is good at using the recipe in treatment of rheumatism. Through compatibility of medicines on the basis of the original prescription(amomum villosum,monkshood,tortoiseshell,liquorice and cortex phellodendri),He can make Qianyang Fengsui Dan have some effects,such as clearing upper-jiao,warming lower-jiao,guiding fire to origin,making Qi belongs to the kidney,supporing Yang Qi and producing Yin jin,etc. It has a good curative effect in treatment of rheumatism,such as heat in the upper and cold in the lower syndrome,and cold-heat complex syndrome resulted by nonhoming lower-jiao archaeus and flaming of asthenia-fire,so which is worth further studying and spreading.%封髓丹首见于明董宿《奇效良方》，潜阳丹为清郑钦安所创，后世医家常将二者合方应用，吴佩衡称之为“潜阳封髓丹”。吴生元教授擅用潜阳封髓丹治疗风湿病，在原方的基础上（砂仁、附子、龟板、甘草、黄柏）加减配伍，能清上温下，引火归元，纳气归肾，助阳生津，对于下元不藏、虚火上浮之上热下寒、寒热错杂之风湿病具有良好的疗效，值得深入研究和推广应用。